BR-101 passes through several major cities, including Natal, Recife, Salvador, Vitória, Rio de Janeiro, São Paulo, and Curitiba, and serves as a vital transportation route for both people and goods. It connects the country's economic and industrial hubs, facilitating trade and commerce.
The road is named after President Eurico Gaspar Dutra, who was in office from 1946 to 1951. It is considered one of the most important highways in Brazil and plays a crucial role in the nation's transportation infrastructure.