Driving Distance: New Orleans, LA to Orange, TX

Distance: 278.6 miles (448.4 km)
Drive time: ~4 hours 15 minutes (normal traffic, I-10 West)

Route

1. I-10 West from New Orleans across Lake Pontchartrain (twin spans).
2. Continue through Slidell, LA → Mississippi Gulf Coast (Bay St. Louis, Gulfport, Biloxi).
3. Cross into Alabama briefly (Mobile Bay via I-10 / George Wallace Tunnel or Bayway).
4. Enter Mississippi → Pascagoula, Moss Point.
5. Cross into Texas at Orange (Sabine River bridge).

Notes

• I-10 is the only direct interstate route.
• Mississippi Gulf Coast casinos (Beau Rivage, Hard Rock) near highway.
• Sabine River bridge can back up; check TXDOT / LADOTD traffic cams.
• Alternative scenic: US-90 along beach (slower, lovely).