- Coal deposits in Illinois, Indiana, and Kentucky,
- Oil and natural gas in Kansas, Oklahoma, and Texas
- Metallic minerals such as copper, lead, zinc, and iron ore in Missouri and Arkansas.
Agriculture:
- Fertile soils in the Midwest region, known as the "Corn Belt" and "Soybean Belt," that support extensive farming of corn, soybeans, and other grains
- Livestock production, particularly cattle and hogs, in the Great Plains region.
Water Resources:
- Major rivers such as the Mississippi, Missouri, and Ohio rivers, which are important for transportation, water supply, and hydroelectric power generation.
- The Great Lakes region, which holds a significant amount of freshwater and supports various economic activities, including fishing, shipping, and tourism.
- Underground aquifers, such as the Ogallala Aquifer, which provide water for agriculture and drinking in the Great Plains region.
Forestry:
- Forests in the Ozark Mountains and Appalachian Mountains, which provide timber for the lumber industry and support diverse wildlife habitats.
Renewable Energy Resources:
- Wind power potential in the Great Plains and Midwest regions
- Solar energy potential in the Southwest and southern Great Plains regions
- Biomass energy potential from agricultural residues and forest products.