Major Cities of the U.S. Midwest

The Midwest (Census Bureau definition) includes 12 states. Key cities by state:

• Illinois: Chicago, Aurora, Naperville, Joliet, Rockford, Springfield, Champaign‑Urbana
• Indiana: Indianapolis, Fort Wayne, Evansville, South Bend, Hammond, Gary
• Iowa: Des Moines, Cedar Rapids, Davenport, Iowa City, Sioux City
• Kansas: Wichita, Kansas City, Topeka, Lawrence, Manhattan
• Minnesota: Minneapolis, St. Paul, Duluth, Rochester, Bloomington
• Missouri: Kansas City, St. Louis, Springfield, Independence, Columbia
• Nebraska: Omaha, Lincoln, Bellevue, Grand Island, Kearney
• North Dakota: Fargo, Bismarck, Grand Forks, Minot, West Fargo
• Ohio: Columbus, Cleveland, Cincinnati, Toledo, Akron, Dayton
• South Dakota: Sioux Falls, Rapid City, Aberdeen, Brookings, Watertown
• Wisconsin: Milwaukee, Madison, Green Bay, Kenosha, Racine

These metros anchor the region’s manufacturing, agriculture, finance, and education sectors.