Yes—the Colorado River forms California's entire eastern boundary from the Nevada tri-point south to Mexico. This 277-mile stretch separates the Golden State from Arizona (mostly) and Nevada (briefly near Laughlin/Bullhead City).
The border follows the 19th-century survey line, not the river's shifting course. Dams (Hoover, Davis, Parker, Imperial, Laguna, Morelos) now control flow entirely. The river rarely reaches the Gulf of California naturally—water is fully allocated.
Under the 1922 Compact & 1944 Treaty, CA receives 4.4 million acre-feet/year (largest single-state allocation), primarily for:
23-year megadrought + overallocation = Lake Mead at ~35% capacity. 2023 agreements cut CA use by 1.6M acre-feet through 2026. The river that built the border now tests the cooperation it requires.