Since Europe is not a city or a specific location, but rather a continent, the distance from Louisville, Kentucky, to Europe can vary greatly depending on the specific destination within Europe.
For example, the distance from Louisville to Lisbon, Portugal, which is the westernmost point of Europe, is approximately 4,004 miles (6,440 kilometers), while the distance from Louisville to Moscow, Russia, which is the easternmost point of Europe, is approximately 5,480 miles (8,819 kilometers).