- Mystic Seaport Museum: This living history museum recreates a 19th-century whaling village with exhibits on shipbuilding, seafaring, and whaling.
- Yale University: Founded in 1701, Yale is one of the most prestigious universities in the country. Visitors can tour the campus and visit the Yale University Art Gallery, which houses a collection of over 100,000 works of art.
- The Mark Twain House & Museum: This museum is dedicated to the life and work of the famous American author Mark Twain. Visitors can tour Twain's home, which is preserved as it was when he lived there, and learn about his life and work.
- The Connecticut Science Center: This interactive science museum offers a variety of exhibits on science, technology, and natural history. Visitors can explore the solar system in the planetarium, watch live animals in the aquarium, and learn about the human body in the Hall of Human Life.
- The Bushnell Center for the Performing Arts: This performing arts center hosts a variety of shows and events, including Broadway musicals, dance performances, and concerts. Visitors can also take a tour of the theater and learn about its history.
- The Wadsworth Atheneum Museum of Art: This museum is home to a collection of over 50,000 works of art, from ancient to modern times. Visitors can view paintings, sculptures, drawings, prints, and photographs from all over the world.
- The Connecticut River Museum: This museum tells the story of the Connecticut River, from its geological formation to its present-day importance as a transportation and recreation resource. Visitors can learn about the river's history, view exhibits on its wildlife, and take a boat ride on the river.
- The New England Air Museum: This museum is dedicated to preserving the history of aviation in New England. Visitors can view a collection of over 100 aircraft, from vintage airplanes to modern jets.
- The Mystic Aquarium: This aquarium is home to a variety of marine life, including sharks, seals, sea lions, and penguins. Visitors can learn about the animals and their habitats, and watch them being fed.
- The Beardsley Zoo: This zoo is home to over 300 animals, from lions and tigers to monkeys and bears. Visitors can learn about the animals and their habitats, and watch them being fed.