Wanderlust World Wanderlust World Traveling between Manhattan and the Bronx is straightforward with multiple public transit and driving options available.
Take the 4, 5, or 6 trains from Grand Central Terminal to 125th Street in Harlem, then transfer to the B or D trains for Bronx destinations. This is typically the fastest and most frequent option.
Express buses (BxM1, BxM2, BxM3) run from Madison Avenue and East 42nd Street directly to various Bronx locations. Local buses (Bx12, Bx19, Bx36) depart from 125th Street and Broadway for different Bronx neighborhoods.
Drive via the Triborough Bridge (Robert F. Kennedy Bridge) or the Harlem River Drive for direct vehicular access between the boroughs.
Subway travel generally offers the most reliable timing, while express buses provide a more direct route for specific destinations.