Donald Sutherland appears in Crossing Delancey (1988), a romantic comedy starring Amy Irving. While primarily filmed in New York City (Lower East Side), second-unit/location scenes were shot in Nova Scotia—likely standing in for coastal or period streetscapes.
Other Sutherland films with Canadian locations include The Disappearance (1977, Montreal), Threshold (1981, Toronto), and Cold Mountain (2003, partly Romania/Canada). But Crossing Delancey is the one most cited for Nova Scotia work.