In 1795, the Spanish ceded the Louisiana Territory back to France. President Thomas Jefferson then sent Meriwether Lewis and William Clark to explore the Louisiana Territory. Lewis and Clark passed through Iowa in 1804 and 1806. Their expedition helped to open up the region to American settlement.
In 1803, the United States government purchased the Louisiana Territory from France. This purchase doubled the size of the United States and included the present-day state of Iowa. American settlers began to arrive in Iowa in the early 1800s. The first permanent settlement was made in 1833 at Burlington. Iowa became a state in 1846.