Kansas City, Missouri (the primary city—Kansas City, Kansas sits adjacent) sits at:
39°N places it on the same parallel as Philadelphia, Denver, Beijing, and Ankara. 94°W aligns with central Mexico, Guatemala, and the Texas Panhandle. It's near the geographic center of the contiguous US (Lebanon, KS is ~250 km west).
The metro spans two states (MO/KS), 14 counties, 8,472 sq mi. The coordinates above reference the traditional downtown (City Hall vicinity). The Missouri River bends just north—historically the city's founding anchor.
GPS navigation, surveying, GIS mapping, satellite targeting, astronomy (culmination calculations), and legal descriptions all use this fixed reference. Relative location ("200 miles west of St. Louis") varies by route; absolute location does not.