The Atacama Desert is located in Chile, South America. It is one of the driest places on Earth, with some parts receiving no precipitation for decades. The Andes Mountains, which run along the western coast of South America, block moisture from the Pacific Ocean from reaching the Atacama Desert. The Atacama Desert is also home to the world's highest volcano, Ojos del Salado. The Amazon River, which is the largest river in the world, is also located in South America.