West Palm Beach, Florida and Tijuana, Baja California are separated by the North American continent. While there is no direct commercial flight between the two cities, the approximate great-circle (straight-line) distance is about 2,200 miles (3,540 kilometers).
By road, the driving distance is roughly 2,500 miles (4,000 kilometers) and would take around 36–40 hours of continuous driving, typically via I-10 West across the southern United States and into Mexico. Actual travel time varies with border crossing waits, traffic, and chosen route.
For precise routing and current conditions, use a mapping service or GPS navigation.