Distance: Omaha, NE to Laramie, WY

The driving distance from Omaha, Nebraska to Laramie, Wyoming is approximately 380 miles (612 km) via I-80 W. Estimated drive time: 5.5–6 hours. Route crosses the Platte River valley, Nebraska Panhandle, enters Wyoming near Pine Bluffs, climbs to Laramie (7,165 ft). Winter: I-80 often closes for high winds/ground blizzards — check WyoRoad / NE 511.