St. Louis, MO Population: 301,578 (2020 Census)

Per the 2020 U.S. Census, the population of the City of St. Louis, Missouri is 301,578.

Context

• Peak: 856,796 (1950) — 65% decline.
• Metro area (MSA): 2,820,253 (2020) — 21st largest US metro.
• Rank: 68th largest city proper (down from 4th in 1900).
• Demographics (2020): 45% Black, 43% White, 4% Hispanic, 3% Asian, 5% multiracial/other.

Why the Drop?

• Fixed city boundaries (61 sq mi) since 1876 — no annexation.
• Suburbanization, white flight, deindustrialization, highway construction.
• Population stabilizing since 2010; downtown residential growth.

St. Louis city ≠ St. Louis region. The metro is 9× the city.