What did the US do after rejection of Permission to build a canal in panama?

The United States responded to the rejection of its request to build a canal in Panama by supporting a rebellion in Panama against Colombia, which at the time controlled the isthmus. The United States provided military and financial assistance to the rebels. As a result of the rebellion, Panama gained independence from Colombia. The Panamanian government then signed a treaty with the United States, granting the United States the right to construct and operate a canal across the isthmus.