What is the approximate time it takes to drive Knoxville Tennessee from Easter New Jersey?

Knoxville, Tennessee is approximately 645 miles from Eastern New Jersey. Assuming an average driving speed of 60 miles per hour without any stops, it would take approximately 10 hours and 45 minutes to drive from Eastern New Jersey to Knoxville, Tennessee. However, this estimate does not account for traffic congestion, weather conditions, rest stops, or potential delays, so the actual travel time may vary.