Will Chevy Colorado Wheels Fit a 2001 Silverado 1500?

No. The bolt patterns differ:

• Chevrolet Colorado: 6-lug (6×139.7 mm / 6×5.5").
• 2001 Silverado 1500: 5-lug (5×139.7 mm / 5×5.5").

The Colorado's 6-lug wheels cannot mount on the Silverado's 5-lug hubs. Adapters exist but are unsafe for load-bearing use. Always match bolt pattern, offset, center bore, and load rating.