Book tickets directly from Rail Europe by calling (888) 382-RAIL or visiting the Web site (see Resources).
Forget Eurail for this route. This is a strictly Eastern European trek, with few discounts offered.
Double-check with the info booths at either of Prague's stations for updates and information before you depart. But show up early, as the stations are perpetually crowded.
Take the sleeper car or first-class upgrade if at all possible, as this long journey can be a bit uncomfortable if you travel in second class.
Use Zagreb, Croatia, as a jumping-off point for other European and Mediterranean destinations, as it lies on the hub of a major inter-continental train crossing.
Since the trip is quite a lengthy one--about 18 hours--you will want to take some good reading materials with you.
Bring snacks and drinks aboard with you, as there is little chance of dining service on the route from Prague to Zagreb.
Ask the locals for information, as most are more than happy to try their English out and will try to help with translations and queries.
Save money and time by hopping the Metro Line C, or Red Line, into Prague's Hlavni Nadrazi Main Station or the smaller Masarykovo Nadrazi.
Settle the fare with cabbies in advance to spare yourself the drama of in-transit fare hikes, which are common among those transporting foreigners in Prague.
