Book your ticket on Amtrak's Web site (see Resources) or by calling (800) USA-RAIL.
Type in your stations for departure (Salem) and arrival (Seattle). If you wish, select dates for each leg as well.
Choose the route you want from Salem to Seattle from the list of options for your date of departure.
Use a promotional code, club affiliation or some other coupon that will give you a discount to save money. You can enter it on the schedules page when prompted.
Carry on medications and snacks with you. Especially if you have dietary restrictions, be sure you pack drinks and food that apply to your needs.
Outline the boarding process for children traveling with you. Make sure they are clear on what is going on so that they are not confused by the hustle and bustle of the stations.
Bring all ID and necessary documents with you and keep them on you at all times. This includes a driver's license, your tickets and important medical information.
Locate destination points on local maps of both cities. This will help you plot out places you'd like to visit during your trip to maximize your time.
Talk to people about your trip to Seattle. Chances are, they have favorite local spots they like to visit and can recommend "insider" advice for a trip there.