Determine how many miles it will take you to cross the desert before setting out. Plan exactly what route you will take and how many miles between gas stations.
Bring a filled gas can with you if there is a possibility of running out of gasoline before reaching the other side of the desert. Most desert crossings make this unnecessary as long as you take advantage of gas stations when you see them. However, if you do bring gas, make sure that the can is sealed tightly and strapped down securely in the trunk or bed of a truck. Gasoline and its fumes are very dangerous so it is best not to travel with it unless absolutely necessary.
Turn off the air conditioning and roll down the windows to prevent an old car from overheating if traveling during the day. Most new cars are able to function properly in high temperatures, but if you choose to use the air, keep your eye on the temperature gauge.
Bring plenty of water for both passengers and as emergency coolant for the car. If you break down, you'll really be glad you did. Also, make sure to have sunscreen, sunglasses and hats for daytime desert crossings. A sandy desert floor can reflect damaging UVA rays, so whether you are in the car or out of it, you'll need protection.
Cross the desert at night to avoid sweltering heat. While a night crossing may prevent you from seeing much of the desert landscape, you'll never see more stars. Note: Be aware that many small gas stations close at night. If you are counting on certain stations, check before you depart on an overnight crossing.