Distance: Grand Forks, ND to Itasca State Park, MN

~148 miles (238 km) via US-2 East → MN-92 East → US-71 North → Park Entrance Road.

Driving time: ~2 hours 45 minutes without stops. Itasca State Park (headwaters of the Mississippi) is in northwestern Minnesota; Grand Forks is on the Red River border. The route crosses the Red River Valley (flat, agricultural) then enters Minnesota's lake-and-forest country.