Driving from Grand Junction, CO to Orlando, FL: Route and Time

Distance: ~2,040 mi (3,283 km).
Time: 30–34 hours driving, plus stops.

General Route

1. Grand Junction → east on I-70 to Denver
2. I-70 through Kansas, Missouri (Topeka, Kansas City, St. Louis)
3. I-44 to Tulsa, OK
4. I-44 through OK, AR → merge I-40 to Memphis, TN
5. I-40 east through TN (Nashville, Knoxville)
6. Into NC on I-40 → US-29N to Charlotte
7. I-77 south to Columbia, SC → into GA
8. I-77 through GA to FL panhandle
9. I-10 east to Orlando

Check traffic, weather, and plan rest stops.