Place each bottle of wine inside an athletic sock. Then wrap each sock tightly in a T-shirt.
Place the wrapped bottles into the large plastic bag. Get as many bottles as you can to fit in each bag as this will help keep them secure.
Fold over the top of the bag and secure it with packing tape. This will help keep the wine from getting onto your clothes should a bottle break.
Open the suitcase. Place shoes and other hard, heavy items in the "bottom" of the case — the part that is at the bottom when you are transporting it, usually where the wheels are.
Place a layer of soft clothing on top of the shoes. Place the wine bag in the center of the suitcase with it oriented so the bottom of the bottles face the bottom of the case.
Fill in the space in front and around the wine bag with the rest of the clothes you are packing and make sure the bag is secure. Close the suitcase and give it a slight shake to make sure the wine bag is secure.
