Prepare for cool temperatures year-round. Although this is California, San Francisco's mercury may only shoot up during limited periods in late spring, late summer and early fall.
Pack business attire that is appropriate to your line of work. Business casual is accepted in most offices.
Pack a leather jacket or wool coat, sweaters and long-sleeve shirts if you plan to be in San Francisco during the fall through spring months. Jeans or khakis are acceptable just about anywhere.
Bring lightweight wool, cotton and fleece garments for easy layering during the summer months. Shorts are a must, but leave other traditional summer items at home.
Bring very comfortable shoes to wear while taking in the sights. Remember, this town has a lot of hills.
Take nice slacks and a blazer (men) if you intend to catch a show, the ballet or opera. Women, opt for a simple dress or skirted outfit. Formal attire is rarely expected.