What is the most popular vacation spot in US?

Orlando, Florida. Orlando, Florida, is the most popular vacation spot in the United States, according to a study by the U.S. Travel Association. The city is home to a number of theme parks, including Walt Disney World, Universal Studios, and SeaWorld, as well as water parks, shopping malls, and other attractions. In 2018, Orlando welcomed more than 75 million visitors, making it the most-visited destination in the country.