Here is a general overview of the route:
1. Naples to Rome: Approximately 215 kilometers (134 miles) and 2 hours 15 minutes of driving time.
2. Rome to Florence: Approximately 285 kilometers (177 miles) and 3 hours of driving time.
3. Florence to Bologna: Approximately 115 kilometers (72 miles) and 1 hour and 30 minutes of driving time.
4. Bologna to Milan: Approximately 210 kilometers (130 miles) and 2 hours of driving time.
5. Milan to Lake Como: Approximately 25 kilometers (16 miles) and 30 minutes of driving time.
Please note that these driving times are approximate and may vary depending on actual road conditions and traffic patterns. It is always advisable to check current traffic information and plan accordingly to ensure a safe and comfortable journey.