Treat yourself to a weekend of pampering and book a reservation at a spa resort. Look for hotels that offer special package deals, such as a girlfriend getaway.
Make a getaway to the coast and reserve a room on the beach. Look for hotels near other amenities, such as golf courses, tennis courts or nature trails. If it's a weekend of rest you want, pack your bikini and book, and spend your day on the sand. Don't forget the sunscreen.
Retreat to the city and spend the weekend shopping with your friend. Enjoy your meals at expensive restaurants and splurge on a pair of new shoes or bag. See a play together, go sightseeing and spend the day at local museums.