Damnation Alley (1969) is a post-apocalyptic novel by Roger Zelazny. The title refers to a treacherous transcontinental route across a devastated United States.
The story centers on Hell Tanner, a convicted criminal offered a pardon if he drives a life-saving vaccine from Los Angeles to Boston through "Damnation Alley"—a narrow, shifting corridor of survivable terrain between lethally radioactive, seismically unstable, and climatically extreme zones.
1977 film Damnation Alley (Jan-Michael Vincent, George Peppard) loosely adapts the novel—adds giant scorpions, changes ending. Book is tighter, darker, more character-driven.
Zelazny's "Alley" became a trope for the "safe path through hell" in post-apocalyptic fiction (cf. The Road, Metro series). The focus isn't just destruction—it's the gauntlet of survival.