- Trinacria: Refers to the triangular shape of the island.
- Sicania: From an ancient people believed to have settled on the island.
- The Pearl of the Mediterranean: Because it is a popular tourist destination.
- The Mother of Colonies: Because it was home to many ancient Greek and Phoenician colonies.
- The Land of the Cyclops: From the mythical one-eyed giants who were said to have lived on the island.
- The Home of the Mafia: Because the Mafia originated in Sicily.
