What direction do you go from Amarillo TX to El Paso TX?

To travel from Amarillo, Texas to El Paso, Texas, you would travel in a southwesterly direction. Amarillo is located in the northern Panhandle of Texas, while El Paso is located in the westernmost part of the state. The most direct route between the two cities is along Interstate 40, which takes you through the cities of Tucumcari, New Mexico, and Santa Rosa, New Mexico, before reaching El Paso.