The mission was located in a verdant valley with a plentiful water supply. The land was fertile and well-suited for agriculture. The mission was also situated near a major Native American trading route, which made it a hub for trade and cultural exchange.
The mission thrived in its early years. By 1834, it had a population of over 2,000 Native Americans. The mission produced a variety of crops, including wheat, corn, beans, and grapes. It also raised cattle, sheep, and horses. The mission also operated a number of workshops, including a blacksmith shop, a carpentry shop, and a tannery.
However, the mission's prosperity did not last. In the 1830s, Mexico gained independence from Spain. The Mexican government secularized the mission, which meant that it was stripped of its land and its Native American converts were freed. The mission fell into disrepair and was eventually abandoned.
In the late 19th century, the mission was restored by the Catholic Church. It is now a National Historic Landmark and is open to the public.