A massive east-west mountain range astride the equator would fundamentally reorganize Earth's climate system:
Trade winds (NE/SE) and equatorial westerlies would be blocked, forced over or around. Jet streams displaced. Walker and Hadley circulations disrupted.
Equatorial rain belt (ITCZ) split or shifted. Tropical wet/dry zones replaced by sharp wet/dry divide. New microclimates at each elevation band.
Wind stress changes → equatorial currents (SEC, NEC, EUC) weakened/reversed. Upwelling patterns shift → marine productivity collapse/redistribution. ENSO dynamics fundamentally altered.
Steep elevational gradients → extreme speciation, sky islands, novel ecosystems. Barrier to latitudinal migration → isolation, endemism.
Monsoons disrupted (no cross-equatorial flow). Tropical cyclones blocked or redirected. Planetary wave patterns altered → teleconnections to mid-latitudes.
Andes (N-S) create Atacama/Amazon contrast. Himalayas (E-W but off-equator) drive monsoon. An equatorial E-W range would be uniquely transformative.
Such a range would make Earth's climate unrecognizable—likely incompatible with current civilization patterns.