Three Major Interstates That Cross Wyoming

Wyoming's wide-open spaces are stitched together by three primary Interstate highways, each serving as a vital artery for commerce, travel, and access to the state's iconic landscapes.

Interstate 80 (East–West, Southern Wyoming)

I-80 traverses the southern tier of the state, connecting Laramie, Rock Springs, and Green River. It's a major freight corridor linking the Midwest to the West Coast.

Interstate 90 (East–West, Northern Wyoming)

I-90 cuts across the north, passing through Gillette, Sheridan, and Buffalo. This route provides access to the Bighorn Mountains and the historic Bozeman Trail.

Interstate 25 (North–South, Eastern Wyoming)

I-25 runs along the eastern plains, serving the capital Cheyenne and Wheatland. It connects Wyoming to Colorado's Front Range and continues south to Albuquerque.

Together, these three Interstates form the backbone of Wyoming's road network, linking its largest cities, energy fields, and gateway communities to Yellowstone and Grand Teton National Parks.