- Suwannee River State Park: This 2,000-acre park is home to the headspring of the Suwannee River, as well as a variety of hiking trails, camping facilities, and swimming areas.
- The Spirit of the Suwannee Music Park: This 800-acre music park hosts a variety of music festivals and events throughout the year, including the Suwannee Springfest and the Spirit of the Suwannee Music and Food Festival.
- The Columbia County Courthouse: This historic courthouse was built in 1904 and is listed on the National Register of Historic Places.
- The Lake City Historic District: This district encompasses over 100 historic buildings, including homes, churches, and commercial buildings, and is listed on the National Register of Historic Places.
- The Lake City Veterans Memorial Park: This park is home to a variety of monuments and memorials honoring veterans from past and present conflicts.