Driving Directions: Nashville, TN to Knoxville, TN
Distance: ~180 miles (290 km) | Time: ~2h 45m – 3h (no traffic)
Route: I-40 East (Direct)
- Start Nashville. Take I-40 East (signs for Knoxville).
- Continue ~160 miles. Pass Crossville (Cumberland Plateau).
- Near Knoxville: Stay on I-40 (do NOT take I-640 unless bypassing downtown).
- Exit for destination: I-40 exits 385–392 serve West Knoxville / University / Downtown.
Key Exits:
- 386B (Pellissippi Pkwy) → Oak Ridge / Maryville
- 387 (Watt Rd) → West Town Mall
- 388 (US-11/US-70) → Downtown / UT
- 389 (I-275) → North Knoxville / Fountain City
Traffic Notes:
- Mon–Fri 7–9am & 4–6pm: Knoxville I-40/I-75 merge (Sharp's Gap) congested.
- Rockslides possible Cumberland Plateau (winter/spring). Check TDOT SmartWay.
Alternative Scenic: US-70 (parallel, slower) through Crossville, Rockwood, Kingston — pretty, not faster.