There is no direct bus connecting Manchester, New Hampshire to Woburn, Massachusetts, but several viable options exist for the ~50-mile journey.
Boston Express + MBTA Route 354
Take Boston Express from Manchester to the Woburn Park & Ride (Anderson Regional Transportation Center). Transfer to MBTA Bus 354 (Burlington Mall - Wellington Station) for the final leg to Woburn. Total time: ~1 hour 15 minutes. Check Boston Express and MBTA schedules for current timing.
Uber/Lyft: Direct door-to-door, ~35-45 minutes depending on traffic. Estimated cost: $45-75 (surge pricing can increase significantly).
Traditional taxi: Similar time, typically $60-90 flat rate or metered.
Take I-93 South directly from Manchester to Woburn (~45-55 minutes, 50 miles). Most straightforward if you have a vehicle. Parking in Woburn varies by destination.
For most travelers, driving or rideshare offers the best time-to-hassle ratio. The bus combination works for budget-conscious travelers with flexible schedules.