- Chennai Mofussil Bus Terminus (CMBT): Located in Chennai, CMBT is one of the largest bus stands in India and serves as a major hub for inter-state and intra-state buses.
- Madurai Central Bus Stand: Situated in Madurai, this is a prominent bus stand that connects Madurai to various cities and towns in Tamil Nadu and neighboring states.
- Villupuram Bus Stand: Located in Villupuram, this bus stand serves as an important transportation hub for travelers heading towards various destinations in the southern and northern districts of Tamil Nadu.
- Coimbatore Central Bus Stand: Situated in Coimbatore, this bus stand is well-connected to major cities across Tamil Nadu and nearby states, including Kerala and Karnataka.
- Trichy Central Bus Stand: Located in Tiruchirappalli, this bus stand caters to passengers traveling within Tamil Nadu and to neighboring states like Kerala, Karnataka, and Andhra Pradesh.
- Salem Central Bus Stand: Situated in Salem, this bus stand serves as a key transportation hub for inter-district and inter-state bus services.
- Nagercoil Central Bus Stand: Located in Nagercoil, this bus stand provides connectivity to various destinations in the southern districts of Tamil Nadu and Kerala.
- Kanyakumari Bus Stand: Situated in Kanyakumari, this bus stand is well-connected to major cities in Tamil Nadu and nearby states, serving as a gateway to the southernmost tip of India.
- Vellore Central Bus Stand: Located in Vellore, this bus stand serves as a major transportation hub for passengers traveling within Tamil Nadu and to neighboring states like Andhra Pradesh and Karnataka.
- Tirunelveli Central Bus Stand: Situated in Tirunelveli, this bus stand is well-connected to cities and towns in Tamil Nadu, as well as to neighboring states like Kerala.