* The Susquehanna River was another important transportation route, and it also provided water power for mills and factories. The Susquehanna Valley was a major agricultural region in colonial Pennsylvania.
* The Allegheny River was a tributary of the Ohio River, and it was used by fur traders and settlers to travel to the Ohio Country.
* The Monongahela River was another tributary of the Ohio River, and it was also used by fur traders and settlers to travel to the Ohio Country.