* Des Moines International Airport (DSM)
* Eastern Iowa Airport (CID)
* Quad City International Airport (MLI)
* Sioux Gateway Airport (SUX)
* Waterloo Regional Airport (ALO)
Railways:
* Amtrak Heartland Flyer: Chicago to Fort Madison
* Amtrak Illinois Zephyr: Chicago to Burlington
* Amtrak Southwest Chief: Chicago to Lamoni
Roads:
* Interstate 29: Missouri River to South Dakota border
* Interstate 35: Des Moines to Missouri border
* Interstate 80: Council Bluffs to Davenport
* U.S. Highway 20: Sioux City to Dubuque
* U.S. Highway 30: Council Bluffs to Clinton
* U.S. Highway 61: Dubuque to Keokuk
* U.S. Highway 63: Burlington to Waterloo
* U.S. Highway 71: Sioux City to Davenport
Buses:
* Burlington Trailways: Statewide service
* Greyhound Lines: Statewide service
* Jefferson Lines: Service to Des Moines, Omaha, and Minneapolis
* Megabus: Service to Chicago, Kansas City, and Minneapolis
Waterways:
* Mississippi River: Navigable from Guttenberg to Keokuk
* Missouri River: Navigable from Sioux City to St. Louis
