Yes, William Miller (1782-1849) was unequivocally opposed to slavery. His abolitionism was rooted in his Baptist faith and biblical literalism — the same hermeneutic that drove his prophetic calculations.
Miller interpreted Scripture as teaching universal human dignity: "God hath made of one blood all nations of men" (Acts 17:26). He viewed slavery as "man-stealing" (Exodus 21:16, 1 Timothy 1:10) — a capital crime under biblical law. His premillennialism (Christ's return to establish justice) reinforced abolition: a just God would not delay judgment on a slaveholding nation.
The Millerite movement (50,000-100,000 adherents, 1830s-1844) overlapped significantly with abolitionism:
Unlike some contemporaries, Miller rejected:
Miller died 1849 — before Civil War. But his movement seeded Seventh-day Adventists (strong abolitionists), and his biblical argumentation influenced political abolitionists. Frederick Douglass noted Millerite sympathy. Modern Adventists cite Miller's abolitionism as doctrinal continuity.
William Miller exemplifies how eschatological conviction can fuel social justice — the same "literal reading" that predicted Christ's return also condemned human bondage.