The Venetian Arsenal, Europe's largest industrial complex, ramped up galley production to counter Ottoman naval power.
Ottomans besieged and captured Nicosia (July 1570); Famagusta fell in 1571. Venice joined the Holy League (Papacy, Spain, etc.) leading to the Battle of Lepanto (1571).
Titian, Tintoretto, Veronese produced masterpieces. Mannerist style thrived; churches and palaces commissioned grand cycles.
New Atlantic trade routes bypassed Mediterranean; Spanish silver influx caused inflation; Venetian commerce declined.
Relative tolerance for Jews, Protestants, Orthodox; but tensions with Papacy over jurisdiction. Patrician dominance challenged by rising merchant class.
Niccolò Tartaglia (ballistics, math) and Giovanni Battista Benedetti (physics, engineering) worked in Venice; cartography and navigation improved.