- Penelope Cruz: Actress
- Javier Bardem: Actor
- Pedro Almodóvar: Film director
- Antonio Banderas: Actor
- Rafael Nadal: Tennis player
- Miguel de Cervantes: Author of "Don Quixote"
- José Ortega y Gasset: Philosopher
- Federico García Lorca: Poet and playwright
- Francisco Goya: Painter
- Salvador Dalí: Surrealist painter
- Santiago Ramón y Cajal: Nobel laureate in medicine
- Severo Ochoa: Nobel laureate in medicine