- Length: 2,340 miles (3,760 km)
- Flows through: 10 states (Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana)
- Notable landmarks: St. Louis Arch, Memphis, New Orleans
2. Missouri River:
- Length: 2,341 miles (3,768 km)
- Flows through: 7 states (Montana, North Dakota, South Dakota, Nebraska, Kansas, Iowa, and Missouri)
- Notable landmarks: Badlands National Park, Mount Rushmore
3. Colorado River:
- Length: 1,450 miles (2,334 km)
- Flows through: 7 states (Colorado, Wyoming, Utah, Arizona, Nevada, California, and Mexico)
- Notable landmarks: Grand Canyon, Hoover Dam
4. Rio Grande:
- Length: 1,900 miles (3,058 km)
- Flows through: Colorado, New Mexico, and Texas (and forms the border between the US and Mexico)
- Notable landmarks: Big Bend National Park, White Sands National Park
5. Columbia River:
- Length: 1,243 miles (2,001 km)
- Flows through: British Columbia, Canada, and Washington, Oregon states in the US
- Notable landmarks: Bonneville Dam, Mount Hood, Columbia River Gorge
6. Ohio River:
- Length: 981 miles (1,579 km)
- Flows through: 6 states (Pennsylvania, Ohio, West Virginia, Kentucky, Indiana, and Illinois)
- Notable landmarks: Pittsburgh, Cincinnati, Louisville
7. Potomac River:
- Length: 405 miles (652 km)
- Flows through: West Virginia, Maryland, Virginia, and Washington D.C.
- Notable landmarks: Mount Vernon, Washington Monument, and National Mall
8. Hudson River:
- Length: 315 miles (507 km)
- Flows through: New York State
- Notable landmarks: New York City, Statue of Liberty, and West Point Military Academy
9. Snake River:
- Length: 1,078 miles (1,735 km)
- Flows through: Wyoming, Idaho, Oregon, and Washington states
- Notable landmarks: Hells Canyon, Shoshone Falls, and Craters of the Moon National Monument
10. Arkansas River:
- Length: 1,469 miles (2,364 km)
- Flows through: Colorado, Kansas, Oklahoma, and Arkansas
- Notable landmarks: Royal Gorge, Wichita, and Little Rock