States Crossed Driving from Miami, FL to Louisville, KY

A direct drive from Miami to Louisville typically passes through five states:

1. Florida
2. Alabama
3. Mississippi
4. Tennessee
5. Kentucky

The most common interstate route (I-75 N → I-24 W → I-65 N) covers ~1,700 km (1,050 miles) and takes about 15–16 hours without stops. Alternate routes may clip Georgia or bypass Mississippi.