Visit the Bedbug Registry at www.bedbugregistry.com. Search for your hotel and find out if bedbugs have been spotted there before. Keep in mind that management may have already resolved the issue. Also, just because bedbugs have been found in one room does not mean they are in every room.
Check your room as soon as you arrive. Leave your luggage by the door or on a luggage rack. Do not place your luggage on the bed or furniture. Take off the sheets and inspect the mattress. Bedbugs tend to hide when disturbed or exposed to sunlight so look for signs of feces. Look for small black dots smaller than the size of a poppy seed. Look in the cracks and crevices of the mattress. Ask for a different room if you find signs of bedbugs.
Keep your clothes in your luggage bag and do not unpack during your stay. Only take out what you are planing to wear or use. This reduces the risk of any bedbugs getting into any of your clothes.
Check your luggage bag for any bedbugs before you leave. Use a flashlight to look in all of your bag's cracks and crevices. Bedbugs are known for their ability to squeeze into tight places.
Wash and dry your clothes as soon as you get home. Do not allow your dirty clothes to sit in a hamper waiting to be washed. Bedbugs will die in the heat of your washer or dryer. They are not able to withstand temperatures higher than 115 or 120 degrees Fahrenheit.