The weight and size regulations for luggage may vary by airline for international travel, but every airline does apply limits to bags, so be sure to check your air carrier's policy beforehand. There are fees for oversized and overweight luggage.
Bags must be accessible for random security screenings, even if they are being checked. TSA regulations in the U.S. state that you may use a TSA-approved lock, for which security officers have a master key. Other countries may require you to remove any locks from your checked baggage.
Firearms and weapons may be packed in checked baggage in most countries, provided you have a permit. Gunpowder, flares and other highly combustible items may not be checked or carried on.