Pick out the clothes you want to wear each day you are gone. Choose lightweight comfortable fabrics that won't wrinkle when they are packed. Fold the clothes as flat as possible and set them aside to add later. Choose a comfortable pair of jeans for each day along with a nice blouse or t-shirt. Choose items that can be changed into quickly and won't wrinkle.
At the bottom of your bag or suitcase, pack the shoes you will need for your long weekend. Bring two pairs of shoes: one you can use for sightseeing and the other pair to wear for a dinner on the town.
Pack socks, underwear and pajamas at the bottom of your suitcase, fitting whatever you can into your shoes to make for more packing room.
Put any accessories into your bag that you might need for your trip. Try to keep them as neat and organized as possible.
Include a book, digital music player and anything else you'll need to keep you occupied during downtime.
Add your clothes to the top of the bag or suitcase and zip it up. Now, you're ready to go.