Is mission la purisima concepion near a presidio?

No. Mission la Purísima Concepción is near the town of Lompoc, California. Presidios were built in Spanish borderlands to protect missions and other settlements. While the mission was initially built as part of the Spanish colonial effort to establish a chain of missions along the El Camino Real (King's Highway) connecting the missions of Alta California, the nearest presidios were Presidio of Monterey and the Presidio of Santa Barbara, which were approximately 150 and 200 miles away, respectively.