Make a list of credit and debit card account numbers and customer care telephone numbers, then pack it separate from your cards. It is a good idea to leave a copy with a family member or trusted friend back home. Take only the cards you will use--major credit and most debit cards are accepted in Mexico--but leave department store and gas cards behind.
Make two copies of your passport--leave one at home in a safe place and take the other with you to Mexico but keep it in a separate location from your passport. It is also a good idea to copy your airline tickets. Leave a copy of your itinerary with a friend or family, or register your trip information with the U.S. State Department's online emergency contact service.
Pack a small umbrella or raincoat because many parts of Mexico have brief afternoon showers. Take along a pair of comfortable shoes for sightseeing, plus sunscreen and a hat, and a sweater or jacket for cool evenings in colonial towns and inland cities.
Assemble a small first aid kit with Band-Aids, antiseptic ointment, alcohol swabs, blister covers and over-the-counter drugs for stomach disorders, diarrhea and pain. Add small packages of tissues and hand sanitizer for bathroom stops.
Wear business attire for posh dining in large cities. Luxury beach resort restaurants are more casual, but avoid jeans and T-shirts at night--men should wear casual pants and a shirt, women a dress or dressy pants and top. Dress modestly when touring churches and shrines--avoid shorts and revealing tops.
Pack an extra duffel bag or knapsack to bring home the Mexican crafts or textiles you purchase.